Edison Investment Research

Aastrom Biosciences

Pharmaceutical & Healthcare

Aastrom Biosciences uses autologous cell therapy to process and inject the patient's own cells. The lead Phase III product aims to reduce the amputation rate in patients with blocked leg arteries: this has $1.25bn sales potential.

Abbey Protection

Financials

Abbey Protection is an integrated specialist insurance and consulting group focused on the delivery of legal and tax related professional fees insurance products and services to the UK SME sector.

Aberdeen New Thai Investment Trust

Investment Trusts

Aberdeen New Thai Investment Trust's investment objective is to provide shareholders with long-term, above-average capital growth through investment in Thailand. Its assets are invested in a diversified portfolio of securities – substantially in the form of equities or equity-related securities such as convertible securities and warrants – in companies spread across a range of industries quoted on the Stock Exchange of Thailand (SET).

Ablynx

Pharmaceutical & Healthcare

Ablynx is a drug-discovery company with a proprietary technology platform. It is developing a novel class of therapeutic proteins called Nanobodies to treat a range of indications. It has six products in clinical development.

Accsys Technologies

Basic Industries

Accsys Technologies is an environmental science and technology company focused on the development, commercialisation and licensing of technologies for use in a wide range of everyday materials. Its main product is the treated softwood Accoya.

Achillion

Pharmaceutical & Healthcare

Acta

Alternative Energy

Acta develops and produces clean technology products for hydrogen generation, power generation and other industrial applications.

Active Biotech

Pharmaceutical & Healthcare

Active Biotech is a Swedish biotech firm focussed on autoimmune/inflammatory diseases and cancer. Its lead projects are laquinimod (partnered with Teva), tasquinimod (partnered with Ipsen) and the immunotherapy ABR-217620 (ANYARA).

Addex Pharmaceuticals

Pharmaceutical & Healthcare

Addex Pharmaceuticals is a Swiss biotech company with a proprietary allosteric modulator discovery platform and a pipeline in CNS, inflammatory and metabolic disorders. It has partnerships with J&J (Ortho-McNeil-Janssen) and Merck & Co.

Advanced Computer Software Group

Technology

Advanced Computer Software Group is a leading provider of software and IT services to the UK health, care and business sectors. Revenue split: Health & Care 21%, Business Solutions 58%, 365 Managed Services 21%.

ADX Energy

Oil & Gas

ADX Energy is an oil and gas exploration business listed in Australia with exploration activities in Tunisia, offshore Italy and Romania. It has mining interests that have been demerged and relisted in Australia under the name of Riedel Resources.

Afferro Mining

Mining

Afferro Mining is a West African iron ore explorer/developer that owns 100% of the 1.42bt Nkout project in Cameroon and 38.5% of the 3.24bt Putu project in Liberia.

African Aura Mining

Mining

African Aura Mining is an advanced-stage exploration company with a focus on West Africa. It has successfully explored for gold and iron ore in Liberia and has recently released a 43-101 resource for the 1Bt Nkout iron ore project in Cameroon. In April 2011, the company will split its gold and iron ore assets into two new entities, Afferro Mining and Aureus Mining, respectively.

African Eagle Resources

Mining

African Eagle is focused on developing its Dutwa nickel laterite project in Tanzania, where a total indicated and inferred resource of 98.6Mt has been defined (according to JORC) at a nickel grade of 0.93% equivalent to 948kt of contained nickel.

Agennix AG

Pharmaceutical & Healthcare

Agennix is a drug development company based in Germany and the US. Its lead product talactoferrin is being developed for the treatment of cancer and sepsis.

Alexza Pharmaceuticals

Pharmaceutical & Healthcare

Alexza Pharmacueticals is US biotech company focused the development of known active agents in its Staccato inhalation system. Its lead product is Adasuve (loxapine, acute agitation); Staccato versions of fentanyl (pain), alprazolam (panic) and zaleplon (insomnia) are dormant.

Alkane Resources

Mining

ALK is a multi-commodity explorer with projects in New South Wales. It owns the Tomingley Gold (100%) and Dubbo rare metal and rare earths (100%) projects and has a 49% (moving to 25%) stake in the McPhillamys Gold project with JV partner Newmont.

Allergy Therapeutics

Pharmaceutical & Healthcare

Allergy Therapeutics is a European-based speciality pharmaceutical company focused on the treatment and prevention of allergy.

Allied Gold Mining

Mining

Allied Gold Mining is a gold explorer-producer. Its main assets are the Simberi Oxide Gold mine in Papua New Guinea and the Gold Ridge mine in the Solomon Islands.

Alpha Strategic

Financials

Alpha Strategic plans to pool a portion of the revenue streams from several single strategy hedge funds.

Altona Energy

Mining

Altona holds a 49% interest in three exploration licences covering 2,500km square in the north of the Permian Arckaringa Basin, South Australia. Its immediate focus is completing a bankable feasibility study for a coal to liquids plus co-generation facility.

Amino Technologies

Technology

Amino Technologies designs and supplies electronic systems, software and consultancy for IPTV (telco triple-play) applications, on-demand video and in-home multimedia distribution.

Amphion Innovations

Investment Companies

Amphion is a technology development and financing firm with a highly focused portfolio of principle investments in the medical and technology sectors.

Amur Minerals Corporation

Mining

Amur Minerals is an exploration and development company focused on base metal projects located in Russia’s far east. The company’s principal asset is the Kun-Manie nickel sulphide deposit, located in the Amur Oblast.

Angel Mining

Mining

Formerly known as Angus & Ross, Angel Mining owns 100% of two mines in Greenland, namely the Nalunaq gold mine and the Black Angel lead/zinc mine. It has now restarted production at Nalunaq and plans to restart production at Black Angel in 2011.

Animalcare Group

Pharmaceutical & Healthcare

Animalcare markets and sells licensed veterinary pharmaceuticals, animal identification products and animal welfare goods for the companion animal market across the UK. Its products are sold in Europe through distributors.

Aquarius Platinum

Mining

Aquarius is the world's fourth largest PGM producer, with five mines in southern Africa: Kroondal (50%), Marikana (50%), Blue Ridge (50%) Everest (100%) and Mimosa (50%) as well as tailings retreatment operations and exploration projects.

Ardea Biosciences

Pharmaceutical & Healthcare

Ardea Biosciences (formerly Intrabiotics Pharmaceuticals) is a US biotech whose work is based on early assets it bought in 2007 from Valeant Pharmaceuticals. Its lead, lesinurad, has just entered Phase III; a Phase II MEK inhibitor anticancer is licensed to Bayer, while NNRTI work in HIV is on hold pending a partnership deal.

Arena Leisure

Travel & Leisure

Arena is the UK’s largest operator of horseracing fixtures with seven racecourses accounting for 26% of racing fixtures. A new hotel opened at Lingfield in May 2010 and Arena has on-going developments at Folkestone, Wolverhampton and Doncaster. It also owns 46% of At The Races.

Ariad Pharmaceuticals

Pharmaceutical & Healthcare

Ariad is a US biotech company with a focus on cancer. Its R&D portfolio includes two projects in Phase III studies: ponatinib for chronic myelogenous leukaemia and ridaforolimus for soft tissue/bone sarcomas. The latter is licensed to Merck & Co.

Ariana Resources

Mining

Ariana is a gold exploration company focused on exploration and development projects in the Republic of Turkey.

ARM Holdings

Electronics & Electrical Equipment

ARM Holdings is a leading player in semiconductor intellectual property. Its customers include the world’s foremost chipmakers.

Arrowhead Research

Pharmaceutical & Healthcare

Arrowhead Research is a US company involved in the development of nano-based technologies in medicine. It has two subsidiaries, Calando (79% owned) and Ablaris (64%), and two minority investments, Nanotope (22%) and Leonardo Biosystems (6%).

Ashley House

Property

Ashley House supplies project management and consultancy services. These are primarily allied to the delivery of new medical facilities for NHS-led primary care, the management of assets and clinical services.

Asian Growth Properties

Property

Asian Growth Properties is an investor and developer of commercial and residential property in Hong Kong and mainland China, ie Chengdu, Nanjing and Guangzhou.

Asterand

Pharmaceutical & Healthcare

Asterand supplies human tissue and tissue-related products as well as tissue testing-based services to R&D companies, many of them big pharmas. It was formed in January 2006 through the reverse takeover of Pharmagene of the UK by the private US firm Asterand.

AstraZeneca

Pharmaceutical & Healthcare

AstraZeneca is a leading multinational pharmaceutical company focussed primarily on gastrointestinal, cardiovascular, respiratory and CNS diseases.

Aureus Mining

Mining

TSX- and AIM-listed Aureus Mining is a West African-focused gold developer/ explorer. Its flagship project is the 1.5Moz New Liberty gold project in Liberia.

AVEO Pharmaceuticals

Pharmaceutical & Healthcare

AVEO Pharmaceuticals is a US biotech company focused on oncology. Tivozanib (triple VEGF inhibitor): Phase III trials for renal cell carcinoma, Phase I/II trials for colorectal, GI and breast cancers and partnered with Astellas ex-Asia. Ficlatuzumab (anti-HGF/c-MET antibody): Phase II trials for non-small cell lung cancer and solid tumours. AV-203 (ErbB3 antibody): preclinical studies for solid tumours and optioned/licensed to Biogen.

Avingtrans

Engineering

Avingtrans is a supplier of highly engineered components and services to the energy, medical, scientific and research communities, traffic management, automation and aerospace industries worldwide.

Avnel Gold Mining

Mining

Avnel Gold owns an 80% interest in the Kalana exploitation permit in south-western Malia. In addition, the company has a 90% interest in the adjacent Fougadian exploration permit.

AB Science

Pharmaceutical & Healthcare

AB Science is a French pharmaceutical company focused on the development of masitinib, an oral tyrosine kinase inhibitor. Eight Phase III trials are ongoing with masitinib across a range of indications, including multiple cancers, RA, asthma and MS. Masitinib was approved in Europe in 2008 as a treatment for tumours in dogs.

Abcam

Pharmaceutical & Healthcare

Abcam produces and sells antibodies and other protein tools for use in research via its website. Its main clients are universities, research institutes and pharmaceutical companies across the world.

Ablon Group

Property

Ablon Group is a leading developer and investor in commercial and residential property in Central & Eastern Europe. It holds a portfolio of 33 assets, 14 income-producing investments and 19 development projects.

Acal

Industrial Support Services

Acal is a specialist provider of technology products and services.

Acencia Debt Strategies Limited

Investment Trusts

Acencia aims to achieve annual returns in excess of 3-month Sterling LIBOR plus 5% over each rolling 3-year period with an annualised monthly standard deviation below 5%.

ACM Shipping Group

Industrial Support Services

ACM is a fully integrated shipbroking business focused principally on the global oil tanker market. It arranges spot and time charters and offers a number of other services, including the sale and purchase of ships.

Actelion

Pharmaceutical & Healthcare

Actelion Pharmaceuticals is a biopharmaceutical company headquartered in Allschwil/Basel, Switzerland, focusing on the discovery, development and commercialization of innovative treatments to serve high unmet medical needs.

Active Energy Group

General Industrials

Active Energy Group (AEG) is evolving into an end-to-end environmental services and solutions business.

Admiral Group

Financials

Admiral was launched in 1993, becoming a public company in 2004. The group’s strategy has been to grow its share of the UK private motor insurance market, focussing on people who would otherwise have difficulty buying insurance. “confused.com” is the largest UK motor insurance aggregator website.

Advanced Medical Solutions

Pharmaceutical & Healthcare

Advanced Medical Solutions is a developer, producer and distributor of an extensive range of wound closure, sealants and wound care products. Its strategy is to develop existing technology platforms in conjunction with a pipeline of new wound closure products.

AFC Energy

Alternative Energy

AFC Energy is an innovative producer of new generation fuel cell systems.

Afren

Oil & Gas

Afren is an independent oil and gas exploration and production company that was founded in 2004. It has a focus on West Africa, with current operations in Nigeria, Gabon, Ghana and Cote d’Ivoire.

African Barrick Gold

Mining

African Barrick Gold was historically the Tanzanian gold mining business of Barrick and is one of Africa’s five largest gold producers with output from four mines, namely Bulyanhulu, Buzwagi, North Mara and Tulawaka.

AGA Rangemaster

Engineering

AGA Rangemaster is an international premium consumer brand owner focused primarily on kitchen appliances and interior furnishings.

Ai Claims Solutions

Financials

Ai Claims Solutions provides credit hire and credit repair as well as other accident management solutions nationally. It represents non-fault drivers and insurers of at-fault drivers.

Algeta

Pharmaceutical & Healthcare

Algeta is a Norwegian biotech company with the leading position in alpha-emitting pharmaceuticals for oncology. Its lead product Alpharadin, in development for treatment of bone metastases arising from prostate cancer, is partnered globally with Bayer.

All Star Minerals

Mining

All Star Minerals is a uranium exploration company focused on Sweden, where it owns 100% of the mineral exploration licences for three projects: Gilpas, Samon and Kuusivaara. The licences cover 111km sq in northern Sweden.

Alliance Pharma

Pharmaceutical & Healthcare

Alliance Pharma is a speciality pharmaceutical company that develops, markets and distributes pharmaceutical products.

Allocate Software

Technology

Allocate Software is the leading provider of software applications designed for workforce optimisation within global organisations employing large, multi-skilled workforces.

Altamir Amboise

Investment Companies

AA is a French limited partnership by shares, listed on NYSE Euronext Paris. 100% of the share capital is floating; 23.08% was held by the partners of Apax as at 31 March 2011. AA has only one listed line of stock, with the unlisted ‘B’ shares purely a mechanism for staff incentivisation via ‘carry’. Altamir Amboise has no debt. Net cash was €57.8m as at 31 March 2011 with €22m in available credit lines. Management fees are payable quarterly in arrears at a rate of 2.0% a year on the company’s total assets. There is no performance fee. The life of the company is indefinite.

Aminex

Oil & Gas

Aminex is involved in the exploration, development and production of oil and gas reserves. Aminex has producing assets in the US, and exploration assets in the East African margin, Egypt and North Korea.

Amlin

Financials

Amlin is an international insurer/reinsurer domiciled in London. It focuses on providing commercial insurance and reinsurance, operating in the UK, within Lloyd’s, Continental Europe and Bermuda.

AmpliPhi Biosciences

Pharmaceutical & Healthcare

AmpliPhi Biosciences is a US/UK biotech company focused on developing of bacteriophages (viruses that infect bacteria) for therapeutic applications. Its lead development product, BioPhage-PA, has potential in treating chronic ear infections.

Andes Energia

Oil & Gas

Andes is an integrated energy company dedicated to oil and gas exploration, electricity generation and distribution in Argentina.

Anglesey Mining

Mining

Anglesey has a 33.0% interest in Labrador Iron Mines, following the full take-up of LIM's recent public offering for C$121m. Anglesey also owns 100% of the Parys Mountain zinc-copper-lead deposit in North Wales.

Antisoma

Pharmaceutical & Healthcare

Antisoma is a UK biotech company which specialised in the development of novel cancer therapies. Following setbacks with its two lead drugs, operations have been scaled back to conserve cash and transactions to maximise value for shareholders is sought.

Arbuthnot Banking Group

Financials

Arbuthnot Banking Group is engaged in retail, investment and private banking and other financial services.

Arden Partners

Financials

Arden Partners is a research-led institutional stockbroking firm. It provides its services to corporate and institutional clients, predominantly in the small and mid cap markets.

Arena Pharmaceuticals

Pharmaceutical & Healthcare

Arena's lead project, lorcaserin (partnered with Eisai), is pending FDA approval for the treatment of obesity. It has a development pipeline of late preclinical and early clinical programmes.

Arian Silver

Mining

Listed on AIM and the TSX, Arian Silver specialises in Mexican silver deposit exploration and development. Its San Jose mine started production in October 2010. Its other projects are Calicanto and San Celso, located in Zacatecas.

Ark Therapeutics Group

Pharmaceutical & Healthcare

Ark Therapeutics specialises in developing products for treating vascular disease, cancer and wound care. The company is a leader in the field of gene-based therapies, and has in-house manufacturing capabilities.

Armour Group

General Industrials

Armour Home designs and distributes a comprehensive upmarket range of home entertainment products, and Armour Auto supplies in-car communications and entertainment components and systems.

Arsenal Holdings plc

Media & Entertainment

AFC Energy is an innovative producer of new generation fuel cell systems.

Ashmore Group

Financials

Ashmore Group is one of the world’s leading emerging market investment managers. Based in London, Ashmore manages US$35.3bn (as at 30 June 2010) in pooled funds, segregated accounts and structured products.

Assura Group

Property

Assura has two businesses: a £353m property portfolio yielding £21m in rents and a profitable £30m turnover growth pharmacy operation. The GP Provider Organisation (GPCo) businesses are now represented by a 24.9% stake in Virgin Healthcare Holdings plus a £4m loan note.

Astex Pharmaceuticals

Pharmaceutical & Healthcare

The newly renamed Astex Pharmaceuticals was formed by the merger of SuperGen and Astex earlier this year. The company is now a UK-US focused oncology drug discovery and development company.

Augean

Industrial Support Services

Augean manages hazardous waste streams through two divisions: Treatment (53% of 2010 sales) and Landfill (47%). The group provides its services at 10 locations across the UK.

Aurizon Mines

Mining

Aurizon Mines is a Canadian gold company with two major assets in the Abitibi region of Canada, namely Casa Berardi and Joanna plus options over a range of other properties.

Avesco Group

Media & Entertainment

Avesco is an international media services group, providing broadcast and audio-visual equipment and services to the corporate, entertainment, sports and broadcast markets worldwide.

Aviva plc

Financials

Aviva provides life and long-term savings products, asset management and all classes of general insurance. Based in the UK, the company employs over 54,000 people and serves more than 50 million customers in the UK, Europe, North America and Asia Pacific.