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Ablynx (ABLX)

Business description

Ablynx is a drug-discovery company with a proprietary technology platform. It is developing a novel class of therapeutic proteins called Nanobodies to treat a range of indications. It has seven products in clinical development.

Share price chart

Share chart

Stock data

Market cap.€107.1m
Last close€2.45
High / Low (52 weeks)€8.8 / €2.2
Stock market listingEuronext Brussels
Forecast net cash (€m)54.7
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & Healthcare

Price performance

%1m3m12m
Actual(23.676)(19.6721)(69.2211)
Relative *(18.7587)(13.7756)(60.0925)

* % Relative to local index

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Y/E Dec Revenue (€m) EBITDA (€m) PBT (€m) EPS (c) P/E (x) P/CF (x)
2010A 31.4 (23.0) (24.0) (56.9) N/A N/A
2011A 21.9 (42.8) (43.3) (99.1) N/A N/A
2012E 26.2 (36.9) (39.1) (89.6) N/A N/A
2013E 36.7 (28.1) (30.8) (70.4) N/A N/A

Last updated on 19/04/2012

Investment summary

Ablynx has developed a broad pipeline using its Nanobody technology in many disease areas. These novel therapeutic proteins have the specificity of monoclonal antibodies and many of the benefits of small molecules. Its lead Nanobody, ozoralizumab (ATN-103 for the $21bn TNF market), successfully completed a Phase II study in rheumatoid arthritis (RA) and Ablynx is looking for a new partner (Pfizer previously had the rights to the product). Ablynx has two other Nanobodies in Phase II trials, ALX-0081/0681 in TTP and ALX-0061 in RA. Ablynx is increasing its business development activities, which should be helped by Novartis's decision to advance its Nanobody into Phase I. It is also more flexible about the terms of potential partnerships and when it will partner programmes. It should have enough cash to operate beyond 2014.

Last updated on 23/04/2012

Industry outlook

There is a strong demand for novel pharmaceutical products. The characteristics of Ablynx's Nanobodies and the initial results from clinical trials mean they have considerable commercial potential in many indications.

Last updated on 23/04/2012

Key management

Edwin Moses, Chairman & CEO
Wim Ottevaere , FD

Company address

Technologiepark 4
9052 Ghent/Zwijnaarde
Belgium
+32 (0)9 262 00 00
View website



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