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Epigenomics (ECX)

Business description

Epigenomics is a German molecular diagnostics company focused on early detection of cancer. Its main product is Epi proColon, a blood-based DNA test for colorectal cancer that uses a sophisticated PCR assay to detect methylated copies of the septin9 gene.

Share price chart

Share chart

Stock data

Market cap.€16.3m
Last close€1.85
High / Low (52 weeks)€7.5 / €1.2
Stock market listingFRA
Forecast net cash (€m)4.4
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & Healthcare

Price performance

%1m3m12m
Actual(12.114)(18.502)(76.052)
Relative *(8.797)(13.808)(72.288)

* % Relative to local index

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Y/E Dec Revenue (€m) EBITDA (€m) PBT (€m) EPS (c) P/E (x) P/CF (x)
2010A 1.8 (10.0) (10.3) (127.5) N/A N/A
2011A 1.4 (7.9) (8.3) (96.9) N/A N/A
2012E 1.0 (8.4) (8.6) (98.5) N/A N/A
2013E 6.8 (4.8) (5.1) (59.3) N/A N/A

Last updated on 09/05/2012

Investment summary

The final module of a US filing for Epigenomics’ blood-based colorectal cancer diagnostic, Epi proColon, hinges on the outcome of a head-to-head comparison study with the FIT assay. The first participant has just been enrolled into this 300-sample trial, which will include up to 75 clinical sites and incorporate elements of prospective and case-control design; data from it will be filed in the second half along with that from an earlier pivotal 7,940-patient study. Epi proColon’s US approval and market take-up are central to the investment case, and inclusion of the Septin 9 test in US coding is a first step to reimbursement.

Last updated on 23/04/2012

Industry outlook

Epi proColon offers patients a simple and convenient alternative to faecal occult blood testing, and should increase compliance for colorectal screening by addressing those individuals who currently do not participate in screening programmes. Epi proLung is an aid in the diagnosis of lung cancer from bronchial lavage using the SHOX2 biomarker.

Last updated on 23/04/2012

Key management

Rolf Krebs, Chairman
Geert Nygaard, CEO
Thomas Taapken, CFO

Company address

Kleine Präsidentenstr.1
10178 Berlin
Germany
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