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Sunesis Pharmaceuticals (SNSS)

Business description

Sunesis Pharmaceuticals is US biotech company focused on the development of anticancer drugs. Its lead compound, vosaroxin, is in a Phase III study for relapsed/refractory AML.

Share price chart

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Stock data

Market cap.US$133.7m
Last closeUS$2.85
High / Low (52 weeks)US$3.1 / US$1.1
Stock market listingNASDAQ
Forecast net cash (US$m)5.7
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & Healthcare

Price performance

%1m3m12m
Actual(6.5574)57.45863.6363
Relative *(3.3996)61.40934.0017

* % Relative to local index

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Y/E Dec Revenue (US$m) EBITDA (US$m) PBT (US$m) EPS (c) P/E (x) P/CF (x)
2010A 0.0 (21.3) (24.6) (593.7) N/A N/A
2011A 5.0 (25.8) (20.1) (43.3) N/A N/A
2012E 0.0 (32.5) (30.5) (65.4) N/A N/A
2013E 0.0 (32.5) (32.9) (70.5) N/A N/A

Last updated on 19/04/2012

Investment summary

Sunesis is moving closer to its key 2012 event - the interim analysis of its pivotal VALOR Phase III study of vosaroxin in relapsed/refractory acute myeloid leukaemia. The 187-event trigger point for the interim analysis is now projected in Q3. The VALOR study has enrolled 260 patients to date and should reach full recruitment of 450 in Q4. Sunesis’s investment case rests entirely on the outcome of the VALOR study and so the interim analysis is of critical importance. Our revised model now indicates a valuation of $300m (of which AML contributes $270m). Sunesis offers a potentially highly geared upside linked to success in the VALOR study, albeit with a high single-product risk. A new $25m royalty funding deal should allow Sunesis to accelerate commercial plans for vosaroxin while extending its cash reach.

Last updated on 23/04/2012

Industry outlook

Of the range of alternative treatments for AML, Dacogen is the most advanced - Eisai/J&J received approval earlier this year for its NDA for the drug. Other programs will report in the near term, including a 300-patient Phase II study of Astellas's Quiztarnib.

Last updated on 23/04/2012

Key management

James Young, Chairman
Daniel Swisher, CEO
Eric Bjerkholt, CFO

Company address

395 Oyster Point Boulevard
Suite 400
South San Francisco
CA 94080
United States
+1 (650) 266-3500
View website



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