<?xml version="1.0" encoding="utf-8"?>
<rss version="2.0"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:sy="http://purl.org/rss/1.0/modules/syndication/"
    xmlns:admin="http://webns.net/mvcb/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:content="http://purl.org/rss/1.0/modules/content/">

    <channel>
    
    <title>Edison Investment Research &#45; recent research</title>
    <link>http://www.edisoninvestmentresearch.co.uk</link>
    
    <dc:language>en</dc:language>
    <dc:rights>Copyright 2012</dc:rights>
    <dc:date>2012-02-08</dc:date>



    <item>
      <title>TiGenix &#45; Cells and marketing</title>
      <link>http://www.edisoninvestmentresearch.co.uk/research/category/tigenix</link>
      <headline>Cells and marketing</headline>
      <description>Edison Investment Research - <![CDATA[Pharmaceutical & Healthcare - TiGenix: TiGenix&#8217;s stem cell therapy, Cx601, is entering Phase III to treat perianal fistulas. Relapsed or Remicade-unresponsive Crohn&#8217;s patients have few other treatment options; excellent Phase II data with the earlier (autologous) product was obtained. TiGenix also has the only EMA approved cell therapy, ChondroCelect, to repair damaged knee cartilage. This could give a strong commercial advantage and might deliver a major sales boost in 2013 if strict ATMP regulations are enforced by the EU. <br />ISIN: BE0003864817]]></description>
      <dc:date>2012-02-06T12:32:57+00:00</dc:date>
    </item>


    <item>
      <title>AB Science &#45; Improving masitinib outlook</title>
      <link>http://www.edisoninvestmentresearch.co.uk/research/category/ab-science</link>
      <headline>Improving masitinib outlook</headline>
      <description>Edison Investment Research - <![CDATA[Pharmaceutical & Healthcare - AB Science: AB Science&#8217;s (AB) investment case is dependent on the successful development of masitinib. Impressive Phase II results showing that the tyrosine kinase inhibitor (TKI) beat Pfizer&#8217;s Sutent in extending overall survival in Gleevec-resistant <a href= <br />ISIN: FR0010557264 ]]></description>
      <dc:date>2012-02-06T11:24:23+00:00</dc:date>
    </item>


    <item>
      <title>Agennix AG &#45; Sepsis trial stopped</title>
      <link>http://www.edisoninvestmentresearch.co.uk/research/category/agennix-ag</link>
      <headline>Sepsis trial stopped</headline>
      <description>Edison Investment Research - <![CDATA[Pharmaceutical & Healthcare - Agennix AG: Agennix has stopped the Phase II/III OASIS trial, following the advice of the study Data Safety Monitoring Board (DSMB). It had observed that the 28-day mortality was greater in patients receiving talactoferrin than those being given placebo. No other unexpected, serious adverse events were observed. Talactoferrin is also in development for non-small cell lung cancer (NSCLC), a very different indication to sepsis, so halting the OASIS trial should not affect the likely outcome of the FORTIS-M Phase III trial in NSCLC in Q212. Our valuation is lowered to &#8364;230m. <br />ISIN: DE000A1A6XX4]]></description>
      <dc:date>2012-02-03T15:11:14+00:00</dc:date>
    </item>


    <item>
      <title>MagForce &#45; Nanomedicine player</title>
      <link>http://www.edisoninvestmentresearch.co.uk/research/category/magforce</link>
      <headline>Nanomedicine player</headline>
      <description>Edison Investment Research - <![CDATA[Pharmaceutical & Healthcare - MagForce: MagForce is aiming to raise &#8364;4.5m through a shareholder rights issue to support the next phase in commercialising its NanoTherm therapy. NanoTherm gained EU approval in 2010 for use in all 27 countries as a treatment for brain tumours but it has taken time to establish treatment centres as well as the required reimbursement procedures. MagForce is now planning a post-approval clinical trial in Germany to help strengthen awareness and experience of the product among key opinion leaders (KOLs), which should eventually drive commercial sales. <br />ISIN: DE000A0HGQF5]]></description>
      <dc:date>2012-02-03T12:05:49+00:00</dc:date>
    </item>


    <item>
      <title>Sangamo BioSciences &#45; Genome editor</title>
      <link>http://www.edisoninvestmentresearch.co.uk/research/category/sangamo-biosciences</link>
      <headline>Genome editor</headline>
      <description>Edison Investment Research - <![CDATA[Pharmaceutical & Healthcare - Sangamo BioSciences: Sangamo shares gained 21% following the announcement of a significant deal with Shire to research novel approaches to treat haemophilia and other monogenic diseases. This provides a welcome vote of confidence in Sangamo&#8217;s core technology of zinc finger DNA-binding proteins (ZFP) after the disappointment in October 2011 when lead candidate SB-509 failed a Phase IIb trial in diabetic neuropathy. The $13m upfront fee will add to already healthy cash reserves of $85m. Phase II data from SB-728 in HIV/AIDS provides a near-term catalyst. <br />ISIN: US8006771062]]></description>
      <dc:date>2012-02-03T11:52:53+00:00</dc:date>
    </item>


    <item>
      <title>ProMetic Life Sciences &#45; Revenue receipts roll in</title>
      <link>http://www.edisoninvestmentresearch.co.uk/research/category/prometic-life-sciences</link>
      <headline>Revenue receipts roll in</headline>
      <description>Edison Investment Research - <![CDATA[Pharmaceutical & Healthcare - ProMetic Life Sciences: Confirmation of near-term purchase orders and service revenues from key customers means that ProMetic Life Sciences has improved visibility on near-term revenue predictability. The company is now emerging from a period where there was a gap in major orders, and expects 2012 to be a stronger year for revenues. This view is supported by the trigger of a $1m upfront payment related to the $2.5m H112 purchase order under its Octapharma supply agreement, and also the achievement of a key milestone with an undisclosed multinational company, leading to confirmed service revenues in 2012 and a potential long-term resin supply agreement. <br />ISIN: CA74342Q1046]]></description>
      <dc:date>2012-02-03T09:06:43+00:00</dc:date>
    </item>


    <item>
      <title>Algeta &#45; Flesh on the bones</title>
      <link>http://www.edisoninvestmentresearch.co.uk/research/category/algeta</link>
      <headline>Flesh on the bones</headline>
      <description>Edison Investment Research - <![CDATA[Pharmaceutical & Healthcare - Algeta: Further data from the interim analysis of the Phase III ALSYMPCA study have confirmed Alpharadin&#8217;s ability to delay patient development of most skeletal-related events, and confirmed its positive adverse event profile. These findings will be particularly important for Alpharadin&#8217;s commercial success. 2012 could see updated ALSYMPCA data, exercise of a co-commercialisation option with Bayer, and regulatory filings. Given the strength of the efficacy data and fast-track status, Alpharadin could be approved by the year end, allowing launch in early 2013. <br />ISIN: NO0010239437 ]]></description>
      <dc:date>2012-02-02T14:53:57+00:00</dc:date>
    </item>


    <item>
      <title>Orexo &#45; Unlocking Abstral&#8217;s value</title>
      <link>http://www.edisoninvestmentresearch.co.uk/research/category/orexo</link>
      <headline>Unlocking Abstral&#8217;s value</headline>
      <description>Edison Investment Research - <![CDATA[Pharmaceutical & Healthcare - Orexo: Orexo&#8217;s shares slipped 11% on news that a preclinical stage collaboration with J&J in arachidonic acid research has been terminated. While scrapping two candidates with the potential to target asthma and COPD is a clear disappointment, Orexo has a number of in-house and partnered programmes that should provide ample compensation and help improve investor sentiment. A rapid expansion of Abstral US sales in a more even playing field and positive clinical and commercial developments with OX219, a Suboxone alternative, offer catalysts in 2012. <br />ISIN: SE0000736415]]></description>
      <dc:date>2012-02-01T16:16:01+00:00</dc:date>
    </item>


    <item>
      <title>Curis &#45; Vismodegib approved</title>
      <link>http://www.edisoninvestmentresearch.co.uk/research/category/curis</link>
      <headline>Vismodegib approved</headline>
      <description>Edison Investment Research - <![CDATA[Pharmaceutical & Healthcare - Curis: Curis has earned a $10m milestone from Genentech (Roche), following the FDA&#8217;s approval yesterday of Erivedge (vismodegib) for advanced inoperable basal cell carcinoma (BCC). This should boost its cash resources to c $40m and put it in a strong position to exploit earlier-stage, multi-targeted drugs such as CUDC-101. Although vismodegib accounts for much of Curis&#8217;s value, we view the investment case as based on the potential of its earlier, clinical-stage compounds. <br />ISIN: US2312691015]]></description>
      <dc:date>2012-01-31T15:41:49+00:00</dc:date>
    </item>


    <item>
      <title>SkyePharma &#45; Two hurdles to jump</title>
      <link>http://www.edisoninvestmentresearch.co.uk/research/category/SkyePharma</link>
      <headline>Two hurdles to jump</headline>
      <description>Edison Investment Research - <![CDATA[Pharmaceutical & Healthcare - SkyePharma: SkyePharma&#8217;s newly appointed CEO, the former finance chief Peter Grant, should be well placed to negotiate the refinancing of the group&#8217;s &#163;83m of convertible bonds. This, together with successfully navigating an arbitration process to secure EU approval of Flutiform, is central to the near-term investment case. Until further details on the timelines emerge, we continue to assume Flutiform launch by the end of 2012. Exparel should be launched in the US early this year, while planned Swiss R&D redundancies will cut &#163;1.8m a year off the company&#8217;s cost base. <br />ISIN: GB00B3BFNB64]]></description>
      <dc:date>2012-01-31T14:37:42+00:00</dc:date>
    </item>


    <item>
      <title>Infinity Pharmaceuticals &#45; Pancreatic setback</title>
      <link>http://www.edisoninvestmentresearch.co.uk/research/category/infinity-pharmaceuticals</link>
      <headline>Pancreatic setback</headline>
      <description>Edison Investment Research - <![CDATA[Pharmaceutical & Healthcare - Infinity Pharmaceuticals: Infinity saw a predictable 40% fall in its share price last week after discontinuing saridegib in pancreatic cancer following an adverse result in its Phase II study. However, investors should look beyond this setback and await the outcome of separate chrondrosarcoma and myelofibrosis studies before passing judgement. Infinity remains well funded &#8211; with c $115m in gross cash and a committed R&D spend from partner Mundipharma of $110m this year &#8211; and has additional trial results due for saridegib as well as for retaspimycin HCl in KRAS-mutant NSCLC. <br />ISIN: US45665G3039]]></description>
      <dc:date>2012-01-30T12:27:00+00:00</dc:date>
    </item>


    <item>
      <title>Pharmaxis &#45; Now breathing easier</title>
      <link>http://www.edisoninvestmentresearch.co.uk/research/category/pharmaxis</link>
      <headline>Now breathing easier</headline>
      <description>Edison Investment Research - <![CDATA[Pharmaceutical & Healthcare - Pharmaxis: Pharmaxis enters 2012 in a promising position after a turbulent 2011. It raised c A$80m in November after the successful reversal, on appeal, of the negative CHMP recommendation for key product, Bronchitol (a dry powder formulation of mannitol) for cystic fibrosis (CF). It now has sufficient funds to see it through Bronchitol&#8217;s Australian and European launches. March/April will be critical as the EMA approval and NDA filing of Bronchitol, and ASM8 Phase IIb asthma data are all due. These catalysts could lead to a recovery in both sentiment and the share price. <br />]]></description>
      <dc:date>2012-01-30T10:44:04+00:00</dc:date>
    </item>


    <item>
      <title>MediGene &#45; Rapid facts expected</title>
      <link>http://www.edisoninvestmentresearch.co.uk/research/category/medigene</link>
      <headline>Rapid facts expected</headline>
      <description>Edison Investment Research - <![CDATA[Pharmaceutical & Healthcare - MediGene: A dynamically designed clinical formulation study of MediGene&#8217;s rheumatoid arthritis project, RhuDex, has begun and should yield data around the middle of this year. If positive, this should allow RhuDex to progress swiftly into further clinical development that could later spur partnering discussions. Our valuation model is unchanged, and the upside for MediGene hinges on a successful partnering deal for EndoTAG-1 and perhaps RhuDex &#8211; its key R&D assets. <br />ISIN: DE0005020903]]></description>
      <dc:date>2012-01-27T08:51:01+00:00</dc:date>
    </item>


    <item>
      <title>4SC &#45; Positive in SHELTER</title>
      <link>http://www.edisoninvestmentresearch.co.uk/research/category/4sc</link>
      <headline>Positive in SHELTER</headline>
      <description>Edison Investment Research - <![CDATA[Pharmaceutical & Healthcare - 4SC: Efficacy data from the Phase I/II SHELTER study of 4SC&#8217;s anticancer agent resminostat strongly back the compound&#8217;s potential in the treatment of sorafenib-resistant hepatocellular carcinoma, and could attract a licensing partner for territories outside Japan. Resminostat comfortably met the targeted 20% rate of 12-week progression-free survival, as well as demonstrating disease stabilisation through the reversal of resistance to the first-line agent, sorafenib. The share price reacted strongly based on deal hopes, and we see further upside ahead. <br />ISIN: DE0005753818]]></description>
      <dc:date>2012-01-24T14:20:30+00:00</dc:date>
    </item>


    <item>
      <title>Ablynx &#45; The refined strategy</title>
      <link>http://www.edisoninvestmentresearch.co.uk/research/category/ablynx</link>
      <headline>The refined strategy</headline>
      <description>Edison Investment Research - <![CDATA[Pharmaceutical & Healthcare - Ablynx: Ablynx is increasing its business development activities and focusing resources on the development of four of its clinical programmes. These activities should enable it to limit its cash burn rate to c &#8364;20-25m, as previously guided. Ablynx is now interested in out-licensing products at earlier stages of development and forming more partnerships, as well as partnering some of its clinical candidates, including its lead product ATN-103. Our valuation is lowered by &#8364;44m to &#8364;452m, but this is still over three times its current market cap. <br />ISIN: BE0003877942]]></description>
      <dc:date>2012-01-23T15:44:11+00:00</dc:date>
    </item>


    <item>
      <title>Synta Pharmaceuticals &#45; Funds to expand studies</title>
      <link>http://www.edisoninvestmentresearch.co.uk/research/category/synta-pharmaceuticals</link>
      <headline>Funds to expand studies</headline>
      <description>Edison Investment Research - <![CDATA[Pharmaceutical & Healthcare - Synta Pharmaceuticals: Synta has closed a $28.6m (net) underwritten stock offering, extending its cash reach into 2013. The fund-raising comes as Synta is embarking on a significant expansion of its development programme for its lead programme, HSP90 inhibitor ganetespib, ahead of the interim read out from the first stage of the GALAXY study in second-line non-small cell lung cancer. Synta continues to indicate a likelihood of closing a licensing deal on Asian rights to ganetespib or global rights to its CRACM (inflammation) assets in early 2012. <br />ISIN: US87162T2069]]></description>
      <dc:date>2012-01-23T15:05:27+00:00</dc:date>
    </item>


    <item>
      <title>Phytopharm &#45; Backing for dual strategy</title>
      <link>http://www.edisoninvestmentresearch.co.uk/research/category/Phytopharm</link>
      <headline>Backing for dual strategy</headline>
      <description>Edison Investment Research - <![CDATA[Pharmaceutical & Healthcare - Phytopharm: Positive preliminary data with Cogane in an amyotrophic lateral sclerosis (ALS) model should increase confidence in Phytopharm&#8217;s strategy to position the chemically related Cogane and Myogane as two projects that can be licensed out separately. The company believes that if it can establish evidence of efficacy in two different models this would support licensing activity separately for neurodegenerative diseases and glaucoma (a glaucoma study should yield data in April). In Parkinson&#8217;s disease, the primary indication for Cogane, a Phase II study continues. <br />ISIN: GB0006869720]]></description>
      <dc:date>2012-01-23T12:35:32+00:00</dc:date>
    </item>


    <item>
      <title>Deltex Medical &#45; 2013 upside potential</title>
      <link>http://www.edisoninvestmentresearch.co.uk/research/category/Deltex-Medical</link>
      <headline>2013 upside potential</headline>
      <description>Edison Investment Research - <![CDATA[Pharmaceutical & Healthcare - Deltex Medical: Deltex anticipates a transitional 2012 and 2013 as the NHS executive starts to use financial incentives to make modern surgical fluid management a routine procedure. As the only NICE recommended product, CardioQ will see strong sales growth from April 2012 onwards. NHS growth is already 20%. In the US, awareness about CardioQ is rising. France could start to develop into a major market. However, for 2011, the trading statement showed a mixed pattern and flat sales with &#163;0.8m cash. <br />ISIN: GB0059337583]]></description>
      <dc:date>2012-01-17T14:16:22+00:00</dc:date>
    </item>


    <item>
      <title>Transgene &#45; Coming of age</title>
      <link>http://www.edisoninvestmentresearch.co.uk/research/category/transgene</link>
      <headline>Coming of age</headline>
      <description>Edison Investment Research - <![CDATA[Pharmaceutical & Healthcare - Transgene: Transgene is an immunotherapy drug development company that could become a fully-integrated pharmaceutical company over the next five years. After many years of development, TG4010 is about to start a Phase IIb/III trial, which could lead to Novartis exercising its option to in-license the product. Its oncolytic virus, JX594 (TG6006), has entered Phase IIb and data from two other Phase II trials could lead to Transgene partnering them. We value Transgene at &#8364;620m. <br />ISIN: FR0005175080]]></description>
      <dc:date>2012-01-17T12:27:24+00:00</dc:date>
    </item>


    <item>
      <title>Hybrigenics &#45; Recruitment complete</title>
      <link>http://www.edisoninvestmentresearch.co.uk/research/category/hybrigenics</link>
      <headline>Recruitment complete</headline>
      <description>Edison Investment Research - <![CDATA[Pharmaceutical & Healthcare - Hybrigenics: Hybrigenics has already completed recruitment of its Phase II in severe psoriasis with inecalcitol, meaning that it now expects to report the results of the trial in June/July 2012 rather than in the autumn. The rapid recruitment into the Phase II trial means it should be easier to detect if inecalcitol is able to treat psoriasis. Inecalcitol has previously been shown to have the potential in castration-resistant prostate cancer (CRPC), and the new data could lead to Hybrigenics out-licensing the product. <br />ISIN: FR0004153930]]></description>
      <dc:date>2012-01-17T09:43:14+00:00</dc:date>
    </item>

    
    </channel>
</rss>
